Bioprocess Engineer- Upstream
BioFactura is seeking highly motivated applicants with an entrepreneurial spirit for a position in our biosimilar and biodefense development programs as well as contract services. We are looking for qualified candidates with a bachelor or master’s degree in biochemical engineering or life sciences with highly relevant skills and bench experience. The selected candidate will support the development and validation of various biologics cell culture processes from the laboratory through Phase I cGMP manufacturing scale. Qualified applicants should be experienced in cell culture including mammalian cell culture of NS0, CHO, and HEK 293 or other immortalized cell lines, selection of stable cell lines, and adaptation/scale-up of cell lines from transfection through shaker culture to small-scale (40 L) bioreactor. Experience with single use bioreactor and/or miniature bioreactors is advantageous but not required. Prior experience with cell culture process development (medium development, feed formulation, culture growth conditions) and spent medium analysis (HPLC, ELISA, enzymatic/kinetic assays) is a plus. Familiarity with DoE implemented through JMP software, a plus. Attention to quality and knowledge of Good Laboratory Practices (GLP) and current Good Manufacturing Practices (cGMP) is beneficial. Experience drafting SOP’s and batch records as well as preparing and delivering oral and written presentations is a plus. Excellent communication skills and the ability to analyze and interpret data, design appropriately controlled resourceful experiments independently, and maintain up-to-date laboratory notebooks are a must. This is an excellent opportunity to gain valuable experience with an innovative and growing Biotech company and build a career in the biopharmaceutical industry. Candidates should feel comfortable working in a high risk/potential high reward environment and able to work flexible hours, including weekends, as project needs are determined.
• Bachelor or Master degree in biochemical engineering or life sciences
• Hands on experience in cell culture and analysis (1-2 years)
• Excellent time management and proven ability to complete projects on time
• Excellent level of initiative, creativity, and quest for knowledge
• Must be organized and self motivated
• Must have excellent communication and writing skills
• Familiarity with Microsoft Office (Word, Excel and Powerpoint etc.)
• Must love to learn!
BioFactura offers a competitive salary with benefits such as:
- Medical, dental, vision
- Health Savings Account
- Retirement plan with company match
- Paid vacation leave